A recent cover article in PCCP by the UCI chemistry professor Sergey Nizkorodov and his collaborators from the Pacific Northwest National Laboratory, Dr. Alexander Laskin and Dr. Julia Laskin, provides a perspective view on the use of high-resolution mass spectrometry for chemical analysis of atmospheric particulate matter. The article describes recent advances in mass-spectrometry methods that have made it possible to simultaneously identify thousands of organic compounds in particulate matter. Understanding molecular composition of organic aerosols at this level of detail was unthinkable just a few years ago. The authors predict an explosive growth of research in this area.