Abstract: 2D electrically conductive metal-organic frameworks (EC-MOFs) represent a distinctive class of porous electronic materials with significant potential in applications ranging from energy storage to advanced electronics. However, their broader impact has been limited by the constrained diversity of structural motifs and chemical functionalities. In this talk, I will present our research efforts demonstrating how molecular approaches drive the advancement of EC-MOFs by tailoring their electronic properties and functionalities. These strategies include novel linker design and post-synthetic modifications that leverage coordination chemistry to introduce functional molecules, enabling precise control over electronic, chemical, physical, and optical properties. By systematically exploring the structure-property-performance relationships, we aim to establish guiding principles for the rational design of high-performance EC-MOF materials tailored for emerging applications.