Artificial Metalloproteins
In another method to control the microenvironment surrounding a metal ion, we take a chemogenetic approach. Here, chemical synthesis of biotinylated ligands allows us to anchor the resultant metal complexes into a protein host. Through genetic manipulation of this host, we can systematically modulate the covalent and noncovalent interactions incurred between amino acid side chains and the metal ion(s).
2012年1月3日火曜日
Artificial Blue Copper Proteins
Biologically Relevant Reactive Intermediates
Biomimetic Multinuclear Active Sites
