Publications

Sustainable polymers that stick inside and out

Zhibin Guan

Science, 2024, DOI: 10.1126/science.adr5857

Efficient and Robust Dynamic Crosslinking for Compatibilizing Immiscible Mixed Plastics through In Situ Generated Singlet Nitrenes

Jordan Castro, Xavier Westworth, Roman Shrestha, Kosuke Yokoyama, and Zhibin Guan

Adv. Mater., 2024, DOI: 10.1002/adma.202406203

Observing the Dynamics of an Electrochemically Driven Active Material with Liquid Electron Microscopy

Wyeth Gibson, Justin T. Mulvey, Swetamber Das, Serxho Selmani, Jovany G. Merham, Alexander M. Rakowski, Eric Schwartz, Allon I. Hochbaum, Zhibin Guan, Jason R. Green, and Joseph P. Patterson

ACS Nano, 2024, DOI: 10.1021/acsnano.4c01524

Nanoantennas Report Dissipative Assembly in Oscillatory Electric Fields

Hong Wei, Héctor Pascual-Herrero, Serxho Selmani, Sebastian Marroquin, Gabriel D. Reginato, Zhibin Guan, and Regina Ragan

J. Colloid Interface Sci., 2024, DOI: 10.1016/j.jcis.2024.03.203

A Vitrimer Acts as a Compatibilizer for Polyethylene and Polypropylene Blends

Kosuke Yokoyama and Zhibin Guan

Angew. Chem. Int. Ed., 2024, DOI: 10.1002/anie.202317264

Multiscale Molecular Dynamics Simulations of an Active Self-Assembling Material

Yuanming Song, Serxho Selmani, J. Alfredo Freites, Zhibin Guan, and Douglas J. Tobias

J. Phys. Chem. B, 2024, DOI: 10.1021/acs.jpcb.3c06572

CryoEM Reveals The Complex Self-Assembly of A Chemically Driven Disulfide Hydrogel

Paul Joshua Hurst, Justin T. Mulvey, Rebecca A. Bone, Serxho Selmani, Redford F. Hudson, Zhibin Guan, Jason R. Green, and Joseph P. Patterson

Chem. Sci., 2024, DOI: 10.1039/D3SC05790A

Fluoride-Catalyzed Siloxane Exchange as a Robust Dynamic Chemistry for High-Performance Vitrimers

Chase Tretbar, Jordan Castro, Kosuke Yokoyama, and Zhibin Guan

Adv. Mater., 2023, DOI: 10.1002/adma.202303280

Waste Free Fully Electrically Fueled Dissipative Self-assembly System

Dipankar Barpuzary, Paul J. Hurst, Joseph P. Patterson, and Zhibin Guan

J. Am. Chem. Soc., 2023, DOI: 10.1021/jacs.2c13140

Precise Control of Dissipative Self-assembly by Light and Electricity

Chunfeng Chen and Zhibin Guan

Chem. Eu. J., 2023, DOI: 10.1002/chem.202300347

Sugar-Fueled Dissipative Living Materials

Hyuna Jo, Serxho Selmani, Zhibin Guan, and Seunghyun Sim

J. Am. Chem. Soc., 2023, DOI: 10.1021/jacs.2c11122

Facile Synthesis of Multifunctional Bioreducible Polymers for mRNA Delivery

James C. Hickey, Paul J. Hurst, Joseph P. Patterson, and Zhibin Guan

Chem. Eu. J., 2022, DOI: 10.1002/chem.202203393

Comparative Investigation of η6-Arene Tethered Ru(II) Complexes with Different Tethered Heteroatoms for Ethylene Polymerization Catalysis: Experimental and DFT Studies

Miguel A. Camacho-Fernandez, Joseph W. Ziller, and Zhibin Guan

Organometallics, 2022, DOI: 10.1021/acs.organomet.2c00267

Electrically Fueled Active Supramolecular Materials

Serxho Selmani, Eric Schwartz, Justin T. Mulvey, Hong Wei, Adam Grosvirt-Dramen, Wyeth Gibson, Allon I. Hochbaum, Joseph P. Patterson, Regina Ragan, and Zhibin Guan

J. Am. Chem. Soc., 2022, DOI: 10.1021/jacs.2c01884

Multifunctional Dendronized Polypeptides for Controlled Adjuvanticity

Zhiyuan Fan, Sharon Jan, James C. Hickey, D. Huw Davies, Jiin Felgner, Philip L. Felgner, and Zhibin Guan Biomacromolecules, 2021, DOI: 10.1021/acs.biomac.1c01052

Chemothermally Driven Out‐of‐equilibrium Materials for Macroscopic Motion

Hurik Muradyan and Zhibin Guan ChemSystemsChem, 2020, DOI: 10.1002/syst.202000024

Multivalent Peptide-functionalized Bioreducible Polymers for Cellular Delivery of Various RNAs

Dong-Chu Yang, Alexander C. Eldredge, James C. Hickey, Hurik Muradyan, and Zhibin Guan Biomacromolecules, 2020, DOI: 10.1021/acs.biomac.0c00211

Self-healing magnetic nanocomposites with robust mechanical properties and high magnetic actuation potential prepared from commodity monomers via graft-from approach

Hurik Muradyan, Davoud Mozhdehi, and Zhibin Guan Polymer Chemistry, 2020, DOI: 10.1039/C9PY01700C

Redox Chemical-Fueled Dissipative Self-Assembly of Active Materials

William Ogden, Zhibin Guan ChemSystemsChem, 2019, 1, e1900030, DOI:10.1002/syst.201900030

Direct Silyl Ether Metathesis for Vitrimers with Exceptional Thermal Stability

Chase A. Tretbar, James A. Neal, Zhibin Guan J. Am. Chem. Soc., 2019, 141 (40), 16595-16599

A Three‐Armed Polymer with Tunable Self‐Assembly and Self‐Healing Properties Based on Benzene‐1,3,5‐tricarboxamide and Metal–Ligand Interactions

Chunmei Li, Jiaojun Tan, Zhibin Guan, Qiuyu Zhang Macromolecular Rapid Communications. 2019

Immunomodulation of the NLRP3 Inflammasome through Structure-Based Activator Design and Functional Regulation via Lysosomal Rupture

Saikat Manna, William J. Howitz, Nathan J. Oldenhuis, Alexander C. Eldredge, Jingjing Shen, Fnu Naorem Nihesh, Melissa B. Lodoen, Zhibin Guan, and Aaron P. Esser-Kahn ACS Central Science. 2018, 8, 982-995.

Recyclable, Strong, and Highly Malleable Thermosets Based on Boroxine Networks

Ogden, William ; Guan, Zhibin J. Am. Chem. Soc., 2018, 140, 6217-6220.

Dendritic Peptide Bolaamphiphiles for siRNA Delivery to Primary Adipocytes

Eldredge, Alexander ; Johnson, Mark ; Cao, Yang ; Zhang, Lin; Zhao, Can ; Liu, Zhengxia ; Yang, Qin ; Guan, Zhibin, Biomaterials. 2018, 178, 458-466.

Silyl Ether as a Robust and Thermally Stable Dynamic Covalent Motif for Malleable Polymer Design

Nishimura, Y.; Chung, J.; Muradyan, H.; Guan, Z. Journal of the American Chemical Society 2017, 139, 14881–14884.

Large Continuous Mechanical Gradient Formation via Metal-Ligand Interactions

Neal, James ; Oldenhuis, Nathan ; Novitsky, Andrea ; Samson, Emil ; Thrift, William ; Ragan, Regina ; Guan, Zhibin

Angew. Chem. Int. Ed., 201756, 15575–15579.

Antisense oligonucleotide and thyroid hormone conjugates for obesity treatment

Cao, Yang ; Matsubara, Tomoko ; Zhao, Gao ; Peng, Linxiu ; Shan, Jinjun ; Liu, Zhengxia ; Yuan, Fang ; Tang, Lingyi ; Li, Peixin; Guan, Zhibin ; Fang, Zhuyuan ; Lu, Xiang ; Huang, Hu ; Yang, Qin Scientific Reports, 2017, 7, 3758-3764.

Phosphine-Iminoquinoline Iron Complexes for Ethylene Polymerization and Copolymerization

Zhang, Dan ; Hou, Wenjun ; Guan, Zhibin ; Huang, Zheng

Organometallics, 2017, 36, 9307.

Focused Library Approach to Discover Discrete Dipeptide Bolaamphiphiles for siRNA Delivery

Eldredge, Alexander ; Johnson, Mark ; Oldenhuis, Nathan ; Guan, Zhibin

Biomacromolecules, 2016, 17, 3138-3144.

Biodegradable Dendronized Polymers for Efficient mRNA Delivery

Oldenhuis, Nathan ; Eldredge, Alexander ; Burts, Alan ; Ryu, Keun ; Chung, Jaeyoon ; Johnson, Mark ; Oldenhuis, Nathan ; Guan, Zhibin

ChemistrySelect, 2016, 1, 4413-4417.

Tuning Dynamic Mechanical Response in Metallopolymer Networks through Simultaneous Control of Structural and Temporal Properties of the Networks

Mozhdehi, Davoud ; Neal, James ; Grindy, Scott ; Cordeau, Yves ; Ayala, Sergio; Holten-Andersen, Niels; Guan, Zhibin

Macromolecules, 2016, 49, 6310-6321.

Fluorocarbon Modified Low-Molecular-Weight Polyethylenimine for siRNA Delivery

Johnson, Mark ; Shon, Judy ; Guan, Brian ; Patterson, Joseph ; Oldenhuis, Nathan; Eldredge, Alexander; Gianneschi, Nathan ; Guan, Zhibin

Bioconjugate Chem., 2016, 27, 1784-1788.

Efficient and selective degradation of polyethylenes into liquid fuels and waxes under mild conditions

Jia, Xiangqing ; Qin,Chuan ; Friedberger, Tobias ; Guan, Zhibin ;d Huang, Zheng

Sci. Adv., 2016, 2, 6.

In situ ultra-small-angle X-ray scattering study under uniaxial stretching of colloidal crystals prepared by silica nanoparticles bearing hydrogen-bonding polymer grafts

Ryohei, Ishige ; Williams, Gregory ; Higaki, Yugi ; Ohta, Noboru ; Sato, Masugu; Takahara, Atsushi and Guan, Zhibin

IUCrJ, 2016, 3, 211-218.

Amino Acid-Functionalized Dendritic Polyglycerol for Safe and Effective siRNA Delivery

Zeng, Hanxiang ; Schlesener, Cathleen ; Cromwell, Olivia ; Hellmund, Markus ; Haag, Rainer, and Guan, Zhibin

Biomacromolecules, 2015, 16, 3869-3877.

Control of hierarchical polymer mechanics with bioinspired metal-coordination dynamics

Grindy, Scott ; Learsch, Robert ; Mozhdehi, Davoud ; Cheng, Jing ; Barrett, Devin ; Guan , Zhibin ; Messersmith, Phillip ; Holten-Andersen, Niels

Nature Materials, 2015, 14, 1210-1216.

Structure-Based Design of Dendritic Peptide Bolaamphiphiles for siRNA Delivery

Zeng, Hanxiang ; Johnson, Mark ; Oldenhuis, Nathan ; Tiambeng, Timothy ; Guan, Zhibin

ACS Central Science, 2015, 1, 303-312.

Enhanced Glassy State Mechanical Properties of Polymer Nanocomposites via Supramolecular Interactions

Hashemi, Amir ; Jouault, Nicolas ; Williams, Gregory ; Zhao, Dan ; Cheng, Kevin ; Kysar, Jeffery ; Guan, Zhibin ; Kumar, Sanat

Nano. Lett., 2015, 15, 5465-5471.

Mechanically Robust and Self-Healable Superlattice Nanocomposites by Self-Assembly of Single-Component "Sticky" Polymer-Grafted Nanoparticles

Williams, Greg ; Ishige, Ryohei ; Cromwell, Olivia ; Chung, Jaeyoon ; Takahara, Atsushi ; Guan, Zhibin

Adv. Mater., 2015, 27, 3934-3941.

Self-healing thermoplastic elastomer brush copolymers having a glassy polymethylmethacrylate backbone and rubbery polyacrylate-amide brushes

Chen, Y. ; Guan, Z.

Polymer, 2015, 69, 249-254 .

Forced Unfolding of Single-Chain Polymeric Nanoparticles

Hosono, Nobuhiko ; Kushner, Aaron M. ; Chung, Jaeyoon ; Palmans, Anja R. A. ; Guan, Zhibin ; Meijer, E. W.

J. Am. Chem. Soc., 2015, 137, 6880-6888.

Highlighted by Nature Chemistry.

Malleable and Self-Healing Covalent Polymer Networks through Tunable Dynamic Boronic Ester Bonds

Cromwell, O. ; Chung, J. ; Guan, Z.

J. Am. Chem. Soc., 2015, 137, 6492-6495.

Multivalent dendritic polyglycerolamine with arginine and histidine end groups for efficient siRNA transfection

Mehrabadi, F. ; Zeng, H. ; Johnson, M. ; Schlesener, C. ; Guan, Z.; Haag, R.

Beilstein J. Org. Chem., 2015, 11, 763-772.

Enhancing Mechanical Performance of a Covalent Self-Healing Material by Sacrificial Noncovalent Bonds

Neal, J. ; Mozhdehi, D. ; Guan, Z.

J. Am. Chem. Soc., 2015, 137, 4846-4850.

Bioinspired Design of Nanostructured Elastomers with Cross-Linked Soft Matrix Grafting on the Oriented Rigid Nanofibers To Mimic Mechanical Properties of Human Skin

Wang, Z.; Jiang, F.; Zhang, Y.; You, Y.; Wang, Z.; Guan, Z.

ACS Nano, 2015, 33, 271-278.

Carbon-based cores with polyglycerol shells - the importance of core flexibility for encapsulation of hydrophobic guests

Lukowiak, M. C.; Ziem, B.; Achazi, K.; Gunkel-Grabole, G.; Popeney, C. S.; Thota, B. N. S.; Bottcher, C.; Krueger, A.; Haag, R.; Guan, Z.

J. Mater. Chem. B, 2015, 3, 719-722.

Self-Healing Multiphase Polymers via Dynamic Metal-Ligand Interactions

Mozhdehi, D.; Ayala, S.; Cromwell, O. R.; Guan, Z.

J. Am. Chem. Soc., 2014, 136, 16128-16131.

Direct correlation of single-molecule properties with bulk mechanical performance for the biomimetic design of polymers

Chung, J.; Kushner, A. M.; Weisman, A. C.; Guan, Z.

Nature Materials, 2014, 13, 1055-1062.

From Racemic Alcohols to Enantiopure Amines: Ru-Catalyzed Diastereoselective Amination

Oldenhuis, N. J.; Dong, V. M.; Guan, Z.

J. Am. Chem. Soc., 2014, 136, 12548-12551.

Multivalent hydrogen bonding block copolymers self-assemble into strong and tough self-healing materials

Chen, Y.; Guan, Z.

Chem. Commun., 2014, 50, 10868-10870.

Ruthenium(IV) Complexes for Ethylene Insertion Polymerization

Friedberger, T.; Ziller, J. W.; Guan, Z.

Organometallics, 2014, 33, 1913-1916.

Catalytic acceptorless dehydrogenations: Ru-Macho catalyzed construction of amides and imines

Oldenhuis, N. J.; Dong, V. M.; Guan, Z.

Tetrahedron, 2014, 70, 4213-4218.

Surfactant-Free Synthesis of Biodegradable, Biocompatible, and Stimuli-Responsive Cationic Nanogel Particles

Urakami, H.; Hentschel, J.; Seetho, K.; Zeng, H.; Chawla, K.; Guan, Z.

Biomacromolecules, 2013, 14, 3682-3688.

Design of supramolecular amino acids to template peptide folding

Mozhdehi, D.; Guan, Z.

Chem. Commun., 2013, 49, 9950-9952.

Direct observation of a cationic ruthenium complex for ethylene insertion polymerization

Camacho-Fernandez, M.; Yen, M.; Ziller, J.; Guan,Z..

Chem. Sci., 2013, 4, 2902-2906.

Multifunctional Dendronized Peptide Polymer Platform for Safe and Effective siRNA Delivery

Hanxiang Zeng, Hannah C. Little, Timothy N. Tiambeng, Gregory A. Williams, Zhibin Guan

J. Am. Chem. Soc., 2013, 135, 4962-4965.

Self-assembly of core-shell nanoparticles for self-healing materials

Yulin Chen, Zhibin Guan

Polym. Chem., 2013, 4, 4885-4889.

Maintaining Functional Islets through Encapsulation in an Injectable Saccharide-Peptide Hydrogel

Sophia W. Liao, Jeffrey Rawson, Keiko Omori, Kohei Ishiyama, Davoud Mozhdehi, Alina Oancea, Taihei Ito, Zhibin Guan, Yoko Mullen

Biomaterials, 2013, 34, 3984-3991.

Self-Healing Supramolecular Block Copolymers

Hentschel, J.; Kushner, A. M.; Ziller, J.; Guan, Z.

Angew. Chem., Int. Ed., 2012, 51, 10561-10565.

Selected as Hot Paper by the editor.

Modulation of Chondrocyte Behavior Through Tailoring Functional Synthetic Saccharide-Peptide Hydrogels

Chawla, K.; Yu, T.-B.; Stutts, L.; Yen, M.; Guan, Z.

Biomaterials. , 2012, 33, 6052-6060.

Olefin Metathesis for Effective Polymer Healing via Dynamic Exchange of Strong Carbon-Carbon Double Bonds

Lu, Y.-X.; Guan, Z.

J. Am. Chem. Soc. , 2012, 134, 14226-14231.

Highlighted by C&EN.

Making Insoluble Polymer Networks Malleable via Olefin Methathesis

Lu, Y.-X.; Guan, Z.

J. Am. Chem. Soc. , 2012, 134, 8424-8427.

Highlighted in JACS Spotlights

Multiphase Design of Autonomic Self-Healing Thermoplastic Elastomers

Chen, Y.; Kushner, A. M.; Williams, G. A.; Guan, Z.

Nature Chem. , 2012, 4, 467-472.

Highlighted by C&EN and Nature Chemistry