PhD defenses.

Catalysis with Ring Strain - Efforts towards Pyrazoles and Cyclic Tripeptides

Abstract:

Pyrazoles and cyclic tripeptides represent two classes of biologically relevant compounds with distinct synthetic challenges. For pyrazoles, the differentiation of two chemically similar nitrogen atoms can be complicated. Cyclic tripeptides, by contrast, are intrinsically strained, making them a largely underexplored yet promising synthetic target. In this defense, I will describe my efforts to address these challenges by leveraging transition-metal catalysis and ring strain.

Chemical Strategies Towards Hybrid One-Dimensional Wires That Approach the Sub-Nanometer Regime

Hybrid organic-inorganic materials offer a powerful platform for synergistically combining molecular tunability with collective, long-range ordered physical states. Yet achieving stable, surface addressable, and low-dimensional extended lattice hybrids—especially in true one-dimensional (1D) form—remains a key challenge.

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