Abstract:

Progress towards enantioselective synthesis of the meroterpenoid rhodatin and the synthesis of the related terpenoid rhodocorane L, both with unique oxidized acorane-type core structures, will be discussed. The spiro[4.5] bicyclic acorane core of each will be formed using asymmetric gold-catalyzed dearomative spirocyclization. This work towards rhodatin explores synthesis and reactivity of ene-diketones, which are rare understudied motifs, towards carbon nucleophiles.

Abstract:

Abstract: Ever since Lappert and coworkers isolated the first examples of crystallographically characterizable La(II) and Ce(II) complexes in 2008, molecular complexes containing rare-earth metals in the +2 oxidation state have been isolated for the rest of the series, except for radioactive Pm.