Abstract: 

Abstract: 

Abstract:

In the last three decades, metal hydride-mediated hydrogen atom transfer (HAT) has seen rapid growth as a mild and chemoselective method for alkene hydrofunctionalization. Our laboratory has extensively developed this chemistry for strategic applications in the synthesis of natural products.

Abstract:

Abstract:  

Species of plants within the Salvia genus of the Lamiaceae family are found on nearly every continent and are renowned for their applications in traditional medicine. These plants possess a variety of chemical constituents that can be divided into several groups, the largest of which are the abietane diterpenoids. The first part of the dissertation describes the abietane diterpenoid known as plebeianiol A and details our synthetic endeavor to elucidate the structure of this natural product.